SEAT - Collaborateurs

  • Gustave Roussy
  • CNRS
  • INSERM
  • ENS
  • Génopôle/Généthon Evry
  • Institut Pasteur
  • Université Pierre et Marie Curie

SEAT - Publications

PAXX and Xlf interplay revealed by impaired CNS development and immunodeficiency of double KO mice
Abramowski M, Etienne O, Elsaid R, Yang J, Berland A, Kermasson L, Roch B, Musilli S, Moussu JP, Lipson-Ruffert K, Revy P, Cumano A, Boussin FD, de Villartay JP Cell Death and Differentiation 2018.

Calibrated mitotic oscillator drives motile ciliogenesis
Al Jord A, Shihavuddin A, Servignat d’Aout R, Faucourt M, Genovesio A, Karaiskou A, Sobczak-Thépot J, Spassky N, Meunier A. Science 2017 (en remerciement).

SEAT

Le Service des Animaux Transgéniques a été ouvert au public en 1992 et fait partie des plateformes de Gustave Roussy (UMS 3655). Il est ouvert à tous les scientifiques, des secteurs publics et privés, désireux d'utiliser des techniques sophistiquées de modification du génome murin.

Pour répondre au mieux aux besoins des chercheurs, le SEAT comprend plusieurs services :

Intégrité scientifique

Scientific Integrity

Scientific integrity is a fundamental value whose defense requires vigilance and requirement from all the actors in research.

The stakes are high:

  • contributing to knowledge
  • providing public confidence in science

Integrity and honesty are requirements applicable to all scientific research.

Gustave Roussy has thus subscribed to the national charter of scientific integrity proposed on June 29, 2016 by Professor Pierre Corvol to Mr. Thierry Mandon, Secretary of State for Higher Education and Research.

CD8 T-cell immunity and immunotherapy in lung cancer

CD8 T-cell immunity and immunotherapy in lung cancer

This group belongs to the UMR 1186 - Integrative tumor immunology and immunotherapy

Despite advances in immunotherapy, a large fraction of cancer patients fails to respond. Immune mechanisms behind this resistance are poorly elucidated. The objective of our research program is to comprehensively characterize and study the role of a new class of white blood cells, called resident memory T cells (TRM), in antitumor immunity and response to cancer immunotherapy.

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