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Oncostat
- Thematic(s)
- Public Health & Epidemiology, Economic Evaluation of Treatments and Biomarkers, Meta-analysis of Treatments and Biomarkers, Clinical Trial Methodology
- Manager(s)
- Stefan Michiels
- Institutional connection
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Gustave Roussy, Inserm, Paris-Saclay University, UVSQ
Summary
The Oncostat team conducts research in the fields of biostatistics, clinical epidemiology, health economics, and data science. The team’s goal is to establish a high level of evidence for precision therapeutic approaches in oncology through methodology and applications.
The team conducts research in four main areas:
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Clinical trial methodology: The team develops new methods for analyzing or designing clinical trials for rare cancers and for integrating biomarkers or artificial intelligence (AI) models into oncology trials.
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Development and validation of biomarkers and risk models: Once a potential biomarker has been identified, rigorous evidence-based evaluation requires confirmation in patient cohort studies, such as the COBLAnCE cohort (Prospective Cohort for an Integrated Study of Bladder Cancers), which we coordinate. The team employs robust statistical methods to identify these biomarkers and develop risk prediction models
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Meta-analysis of treatments and biomarkers: Meta-analyses of individual-level data are essential tools for providing a high level of evidence regarding the efficacy and toxicity of anticancer treatments in patient subgroups defined by a molecular profile. The meta-analysis databases also give rise to associated methodological research.
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Economic evaluation of strategies combining biomarkers and treatments: Therapeutic advances are accompanied by rising prices for drugs and innovative technologies, raising questions about the sustainability of healthcare spending. Research in this area is needed to inform public policymakers regarding resource allocation and equitable patient access.
Team members
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Stefan MICHIELS - Team Leader
Director of Research and Equivalent Positions, Gustave Roussy
AUPERIN, Anne
Hospital Physician, Gustave Roussy
BARGAIN Charlotte
Design Engineer or equivalent, Gustave Roussy
Arnaud BAYLE
University Lecturer and Hospital Practitioner, Paris-Saclay University
BENHAMOU Simone
Emeritus Research Director, Gustave Roussy
BLANCHARD Pierre
University Professors and Hospital Practitioners, Paris-Saclay University
BONASTRE Julia
Research Associate and Equivalents, Gustave Roussy
Isabelle Borget
University Professors and Hospital Practitioners, Paris-Saclay University
CARNET LE PROVOST, Killian
Ph.D. Candidate, AP-HP
Dan CHALTIEL
Hospital Physician, Gustave Roussy
Alexis COCHARD
Design Engineer or equivalent, Gustave Roussy
Nathalie COZIC
Research Engineer or equivalent, Gustave Roussy
Damien Drubay
Research Associate or equivalent, Gustave Roussy
Elie El Rassy
Ph.D. Candidate, Gustave Roussy
Farah ERDOGAN
Ph.D. candidate, Inserm
FARON Matthieu
Hospital Physician, Gustave Roussy
Thomas Filleron
Researcher and equivalent positions, ONCOPOLE CLAUDIUS REGAUD - TOULOUSE
Stéphanie FOULON
Hospital Physician, Gustave Roussy
Alderic Fraslin
Design Engineer or equivalent, Gustave Roussy
Robabeh Ghodssighassemabadi
Research Engineer or equivalent, Gustave Roussy
JONAS Sarah-Flora
Research Engineer or equivalent, Gustave Roussy
Eleni Karamouza
Research Engineer or equivalent, Gustave Roussy
KOUDOU Akoli Yves
Design Engineer or equivalent, Paris-Saclay University
LE DELEY Marie-Cécile
University Associate Professor—Hospital Practitioner, OSCAR LAMBRET
LE TEUFF Gwenael
Research Fellow or equivalent, Gustave Roussy
Anne LOURDESSAMY
Design Engineer or equivalent, Gustave Roussy
MAMANN Aaron
Ph.D. Candidate, Paris-Saclay University
Aldrine Manzanilla
Ph.D. student, Paris-Saclay University
MARELLI Cristina
Ph.D. student, Paris-Saclay University
MONNEREAU Matthias
Ph.D. student, PRIVATE
Arnaud PAGES
Hospital Physician, Gustave Roussy
PAPER, Laura
Ph.D. student, Gustave Roussy
Lou-Anne PERETTI
Ph.D. candidate, Paris-Saclay University
ROUSSEAU Adrien
Ph.D. student, Gustave Roussy
SEDKI Mohammed
Assistant Professor, Paris-Saclay University
Noémie SIMON-TILLAUX
Hospital Physician, Gustave Roussy
Chloe Szurewski
Ph.D. Candidate, Paris-Saclay University
Marie-Laure TANGUY
Research engineer or equivalent, Gustave Roussy
Matthieu TEXIER
Research Engineer or equivalent, Gustave Roussy
Key publications
Contacts
- Phone
- Administrator: 01.42.11.41.40
