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Clinical Trials and Research for Adolescents and Young Adults
Like adult patients, adolescents and young adults with cancer may be eligible to participate in a clinical trial.
What is a clinical trial?
Although current treatments allow for the cure of the majority of adolescents and young adults with cancer, certain subtypes of the disease remain associated with a poor prognosis. Furthermore, even after remission, some patients may continue to experience side effects—sometimes significant ones—related to the tumor itself or to the treatments they received.
In this context, clinical trials aim to improve the management of the most complex cases while reducing adverse effects. Conducted according to strict protocols, these clinical trials ensure the safety of participants while adhering to rigorous scientific and ethical standards.
→ Learn more about clinical research [note: link to be added]
Three Types of Clinical Trials for Adolescents and Young Adults
Depending on their age at the time of enrollment in the trial, adolescents and young adults may be eligible to participate in a clinical trial open to adults, children, or both.
Understanding Clinical Trials Through Video
Clinical Trials at Gustave Roussy
As a pioneer in the development of clinical trials, Gustave Roussy places particular emphasis on making new treatments accessible to all cancer patients who could benefit from them.
Doctors and teams from several departments at Gustave Roussy participate in clinical trials:
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Pediatric oncologists from the Department of Pediatric and Adolescent Oncology
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The team from the Specific Interdisciplinary Care Program for Adolescents and Young Adults (SPIAJA)
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Clinical trial specialists from the Department of Therapeutic Innovation and Early-Phase Trials (DITEP)
These experts are working on multiple fronts to facilitate patients’ access to new treatments:
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Local
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National, with the French Society for Childhood and Adolescent Cancers and Leukemias (SFCE)
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European, in partnership with the ITCC (Innovative Therapies for Children and Adolescents with Cancer) network and the ACCELERATE platform
Strategies Tailored to Each Situation
Different situations can lead to a clinical trial, each of which has a specific objective.
When treating certain highly aggressive tumors, experts at Gustave Roussy use new drugs or new combinations of drugs to improve treatment effectiveness.
To prevent long-term effects related to the tumor and its treatments, physician-researchers are working to reduce the use of treatments associated with a risk of complications in patients with certain types of tumors.
The mechanisms underlying the development and progression of cancers are highly diverse and vary from one patient to another. Each tumor has its own unique characteristics. The teams at Gustave Roussy use molecular profiling to offer patients a treatment tailored to the genetic characteristics of their tumor.
Join a clinical trial
Many clinical trials are open to adolescents and young adults.
