Genome Plasticity and B cells

Group leader
Dr Saïd Aoufouchi

Pavillon de recherche 2, Level 3

 

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Genome Plasticity and B cells

Major publications since 2009

  • Xavier Renaudin, Jean-Hugues Guervilly, Said Aoufouchi, and Filippo Rosselli.Proteome-wide analysis unveils a FANCA-modulated neddylation signaling pathway involved in CXCR5 membrane trafficking and cell mobility. 
  • J Cell Sci. 2014 Aug 15;127(Pt 16):3546-54. doi: 10.1242/jcs.150706. Epub 2014 Jul 11.
  • Nguyen TV, Riou L, Aoufouchi S*, Rosselli F*. J Exp Med. Fanca deficiency reduces A/T transitions in somatic hypermutation and alters class switch recombination junctions in mouse B cells. 2014 Jun 2;211(6):1011-8. doi: 10.1084/jem.20131637. Epub 2014 May 5. (* corresponding authors)
  • Gineau L, Cognet C, Kara N, Lach FP, Dunne J, Veturi U, Picard C, Trouillet C, Eidenschenk C, Aoufouchi S, Alcaïs A, Smith O, Geissmann F, Feighery C, Abel L, Smogorzewska A, Stillman B, Vivier E, Casanova JL, Jouanguy E. J Clin Invest.
  • Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency. 2012 Mar 1;122(3):821-32. doi: 10.1172/JCI61014. Epub 2012 Feb 22.
  • S, Aoufouchi S, Weill JC, Reynaud CA. AID and partners: for better and (not) for worse.
  • Storck.Curr Opin Immunol. 2011 Jun;23(3):337-44. Epub 2011 Mar 24. Review
  • Faili A, Stary A, Delbos F, Weller S, Aoufouchi S, Sarasin A, Weill JC, Reynaud CA.
  • A backup role of DNA polymerase kappa in Ig gene hypermutation only takes place in the complete absence of DNA polymerase eta. 
  • J Immunol. 2009 May 15;182(10):6353-9.
  • ATM localization and gene expression in the adult mouse eye.. 2009;15:393-416. Epub 2009 Feb 20 
  • Reynaud CA, Delbos F, Faili A, Guéranger Q, Aoufouchi S, Weill JC  Competitive repair pathways in immunoglobulin gene hypermutation.. 
  • Philos Trans R Soc Lond B Biol Sci. 2009 Mar 12;364(1517):613-9. Review 
  • Gueranger Q, Stary A, Aoufouchi S, Faili A, Sarasin A, Reynaud CA, Weill JC. Role of DNA polymerases eta, iota and zeta in UV resistance and UV-induced mutagenesis in a human cell line. 
  • DNA Repair (Amst). 2008 Sep 1;7(9):1551-62. Epub 2008 Jul 21. 
  • Aoufouchi S, Faili A, Zober C, D'Orlando O, Weller S, Weill JC, Reynaud CA. Proteasomal degradation restricts the nuclear lifespan of AID. 
  • J Exp Med. 2008 Jun 9;205(6):1357-68. Epub 2008 May 12.
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