Professor Florent Ginhoux

Florent Ginhoux holds a degree in biochemistry from Pierre and Marie Curie University (Paris VI) and a postgraduate qualification in immunology from the Institut Pasteur. He obtained his PhD in 2004, which he completed in the immunology team at Généthon (Évry). He then joined Miriam Merad’s laboratory at the Mount Sinai School of Medicine (MSSM) in New York, where he studied the ontogeny and homeostasis of skin dendritic cells, particularly Langerhans cells and microglia.

In 2008, Florent Ginhoux became an assistant professor in the Department of Gene and Cell Medicine at MSSM and a member of its immunology institute. In May 2009, he joined the Singapore Immunology Network (SIgN) / A*STAR as a principal investigator, and four years later was selected for the EMBO Young Investigator Programme (YIP). Since 2015, he has also been a visiting associate professor at the Shanghai Institute of Immunology (Shanghai Jiao Tong University, China). In 2021, he joined Gustave Roussy to lead a research laboratory within Unit U1015 directed by Laurence Zitvogel.

His research focuses on the ontogeny and differentiation of macrophages and dendritic cells, with a particular emphasis on microglial development using induced pluripotent stem cell (iPSC) technologies. Together with his team, he has been developing a pioneering approach over the past several years: brain immuno-organoids. These reprogrammed stem cells make it possible to study the development of childhood and adolescent brain tumours, with the aim of identifying more effective therapies for high-grade gliomas.

Florent Ginhoux has been listed among the world’s most highly cited researchers (Clarivate Highly Cited Researchers List) since 2016.