Translational Research in Hematology

Head of the platform
Stéphane De Botton

Lab manager
Cyril Quivoron

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Translational Research in Hematology

Activities

Reception and qualification of biological samples collected from patients with hematological malignancies treated at Gustave Roussy.  Translational research projects are addressed after validation by lab steering committee. Research projects are proposed by the Hematology Committee or DITEP members; contracts are validated by Gustave Roussy Transfert.

  • Hematopoietic cells selection/enrichment and immunophenotyping.
  • Nucleic acid extraction (as well as cell-free circulating tumoral DNA).
  • Normal/tumoral matched sequencing (NGS, scDNAseq, ddPCR, RT-MLPA…).
  • Primary cell culture and drug testing in vitro.
  • Patients-derived xenograft and drug testing.

Equipments

  • GentleMACS Dissociator, Miltenyi Biotec
  • AutoMACS Pro Separator Instrument, Miltenyi Biotec
  • Tapestri, Mission Bio
  • Cell culture (hood, incubator, centrifuge)

 

 

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