Major publications

• Circulating tumor cell copy-number heterogeneity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors. Oulhen M, Pawlikowska P, Tayoun T, Garonzi M, Buson G, Forcato C, Manaresi N, Aberlenc A, Mezquita L, Lecluse Y, Lavaud P, Naltet C, Planchard D, Besse B, Farace F. NPJ Precis Oncol. 2021 Jul 16;5(1):67. doi: 10.1038/s41698-021-00203-1.PMID: 34272470

Team members

• Head of the platform
  Françoise Farace, PhD/HDR
  Email

• Engineer
  Patrycja Pawlikowska, PhD,

• Engineer
  Marianne Oulhen

• Technician
  Agathe Aberlenc

• PhD student
  Tala Tayoun

   

Equipment

• CellSearch platform for CTC and CEC enrichment and detection
• ISET filtration enrichment system for rare circulating cells (RareCells)
• Parsortix enrichment microfluidic system for CTCs (Angle) 
• VyCAP system for rare cell filtration 
• Automated filtration system Versant kPCR for rare cells (Siemens) 
• ARIOL scanner (LEICA microsystems) 
• ARIOL stations for microscopy image analysis (LEICA microsystems)
• Fluorescence microscope (Nikon)
• Laser microdissecteur (LEICA microsystems)

Activities

The platform is dedicated to the analysis of rare blood cell components such as circulating tumor cells (CTC) and circulating endothelial cells / progenitors (CEC / CEP), used as biomarkers in clinical trials.

Newsletter Good to Know : l'actualité scientifique en cancérologie, vue par Gustave Roussy.