CD8 T-cell immunity and immunotherapy in lung cancer
This group belongs to the UMR 1186 - Integrative tumor immunology and immunotherapy
Despite advances in immunotherapy, a large fraction of cancer patients fails to respond. Immune mechanisms behind this resistance are poorly elucidated. The objective of our research program is to comprehensively characterize and study the role of a new class of white blood cells, called resident memory T cells (TRM), in antitumor immunity and response to cancer immunotherapy.