Lab members

• Fawzia Louache, DR2 Inserm, Group leader
• Virginie Joulin, DR2 Inserm, 
• Monika Wittner, CR1 CNRS, 
• Paul Coppo, PU-PH Paris 6, 
• Yanyan Zhang, Post-doc 
• Mallorie Mangean, PhD student
• HE Liang, PhD student
• Eric Grignano, Master 2

Recent publications

• Bouchekioua A, Scourzic L, de Wever O, Zhang Y, Cervera P, Aline-Fardin A, Mercher T, Gaulard P, Nyga R, Jeziorowska D, Douay L, Vainchenker W, Louache F, Gespach C, Solary E, Coppo P. JAK3 deregulation by activating mutations confers invasive growth advantage in extranodal nasal-type natural killer cell lymphoma. Leukemia. 2014;28(2):338-48. 

The hematopoietic niche group

Hematopoietic tissue aging

This group belongs to the UMR 1287 - Hematopoietic stem cells and the development of myeloid malignancies

• Guillaume Montagnac, PI Inserm
• Nadia Elkhatib, Inserm staff scientist (CRCN)
• Francesco Baschieri, post-doc
• Kseniia Porshneva, post-doc
• Enzo Bresteau, post-doc
• Nathalie Ly, Engineer
• Julie Bruna-Gauchoux, PhD student
• Samuel Tettarasar, PhD student

Major publications

• Lock JG, Baschieri F, Jones MC, Humphries JD, Montagnac G, Strömblad S, Humphries MJ. Clathrin-containing adhesion complexes. J Cell Biol. 2019 Jul 1;218(7):2086-2095. doi: 10.1083/jcb.201811160. Epub 2019 Jun 17.
• Baschieri F, Dayot S, Elkhatib N, Ly N, Capmany A, Schauer K, Betz T, Vignjevic DM, Poincloux R, Montagnac G. Frustrated endocytosis controls contractility-independent mechanotransduction at clathrin-coated structures. Nat Commun. 2018 Sep 20;9(1):3825. doi: 10.1038/s41467-018-06367-y.

Endocytosis, cytoskeleton and cell migration

This team belongs to the UMR 1279 - Tumor cell dynamics

The overall objective of our lab is to understand how the mechanical properties of the tumoral environment influence cancer cell migration.