UMR 1186 - Integrative tumor immunology and immunotherapy
Our laboratory highlighted several constitutive elements of the tumor environment (TME) involved in the regulation of antitumor T-cell response, in particular:
The UMR S1138, Cordeliers Research Centre, is under the aegis of the University of Paris Descartes, Inserm and the Pierre and Marie Curie University (UPMC) and has links with CNRS and the Ecole Pratique des Hautes Etudes (EPHE) (Practical Higher Studies School).
One of the teams from the UMR S1138, « Metabolism, cancer and immunity » is located on the Gustave Roussy site. It is directed by Professor Guido Kroemer.
Golan, T., Parikh, R., Jacob, E., Vaknine, H., Zemser-Werner, V., Hershkovitz, D., Malcov, H., Leibou, S., Reichman, H., Sheinboim, D., Percik, R., Amar, S., Brenner, R., Greenberger, S., Kung, A., Khaled, M., and Levy, C. (2019) Adipocytes sensitize melanoma cells to environmental TGF-beta cues by repressing the expression of miR-211. Sci Signal 12