Traitement des sarcomes et tumeurs complexes

La chirurgie est la pierre angulaire du traitement curatif des sarcomes, quand celle-ci est possible et que la maladie n'est pas métastatique. Elle peut être associée à de la radiothérapie et/ou à de la chimiothérapie.

Sarcoma and complex tumour

back to job offer list

back to clinical trials

Treatment of sarcomas and complex tumours

Gustave Roussy treats patients with soft tissue and bone sarcomas, desmoid tumours, gastrointestinal stromal tumours (GIST) and other complex tumours (chordomas and PEComas).
Sarcomas are tumours which arise in connective tissue (mesenchyme). There are a number of types of mesenchymal tumours whose consequences and severity vary greatly depending on:

Mechanisms of DNA Repair and Carcinogenesis - Lab members

back to job offer list

back to clinical trials

Lab members

Murat SAPARBAEV, Research Director, DR1, CNRS;
Alexandre A. ISHCHENKO, Research Director, DR2, CNRS;
Regina GROISMAN, CRCN, INSERM;
Sophie GAD-LAPITEAU, Professor, EPHE ;
Sophie COUVE, Assistant professor, EPHE ;
Flore RENAUD-PAITRA, Assistant professor, EPHE ;
Sophie FERLICOT, PU-PH, clinicien, Université Paris-Saclay ;
Dominique BLUTEAU, Assistant professor, EPHE ;
Kévin BOQUET, technician, EPHE;
Victoria POILLERAT, PhD student, EPHE;

Mechanisms of DNA Repair and Carcinogenesis - Publications

back to job offer list

back to clinical trials

Major publications

Matkarimov, B.T., Zharkov, D.O., and SAPARBAEV, M.K. (2019) Mechanistic insight into the role of Poly(ADP-ribosyl)ation in DNA topology modulation and response to DNA damage. Mutagenesis, Nov 29. pii: gez045. doi: 10.1093/mutage/gez045/5646155.