Cytometry & Mass imaging - Team members

Cytometry & Mass imaging - Team members

Operational manager:
Philippe Rameau (Research Engineer)
Tel. 01.42.11.51.38
philippe.rameau@gustaveroussy.fr

Cyril Catelain (Research Engineer)
Tel. 01.42.11.51.38
cyril.catelain@gustaveroussy.fr

Cytometry & Mass imaging - Publications

Cytometry & Mass imaging - Publications

  • Low Doses of Radiation Increase the Immunosuppressive Profile of Lung Macrophages During Viral Infection and Pneumonia Meziani L, Robert C, Classe M, Da Costa B, Mondini M, Clémenson C, Alfaro A, Mordant P, Ammari S, Le Goffic R, Deutsch E.. Int J Radiat Oncol Biol Phys. 2021 Aug 1;110(5):1283-1294. doi: 10.1016/j.ijrobp.2021.03.022. Epub 2021 Mar 13. PMID: 33722770; PMCID:PMC7954779.

    Cytometry & Mass imaging - Equipments

    Cytometry & Mass imaging - Equipments

    Mass cytometer HELIOS (Fluidigm)

    As a complementary tool to flow cytometers, the mass cytometer considerably increases the number of parameters that can be analyzed (>40), while eliminating the problems of overlapping fluorescence spectrums observed with conventional cytometry.

    Cytometry and Mass imaging - Activities

    Cytometry & Mass imaging - Activities

    Training and coaching

    • Flow, spectral and mass cytometry
    • Cell sorting and single-cell isolation
    • Mass imaging for molecular, cellular and functional spatial mapping of cells and tissues
    • Bioinformatics adapted to the unsupervised analysis of cytometry and imaging data.

    Design of experimental procedures

    Research in Immunotherapy

    PREMIS: A programme dedicated to immunotherapy toxicity

    By stimulating patients' immune systems, immunotherapy drugs can generate autoimmune side effects, especially when used in combination, which can affect several organs, sometimes irreversibly. Yet there are no biomarkers to identify patients at risk of developing severe complications. Their discovery is a major objective in improving the management and safety of treated patients.

    Prism

    A flagship collaborative programme to virtualize cancer

    Logo Prism

    The Data Science Programme

    Cancer is a complex disease. It is vital to cross-reference the opinions of professionals in the various care and research disciplines (oncologists, biologists, geneticists, anatomopathologists and radiologists, etc.) in order to gain the most comprehensive overview and offer each patient the best therapeutic option or direct them towards an appropriate clinical trial. The aim of the "DATA SCIENCE" programme is to draw on a large volume of data relating to the diagnosis and management of previously treated patients to facilitate comparison.

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