Lab members

Team leader: Anne Dupressoir

Researchers :

• Anne DUPRESSOIR, CRHC Inserm
• Odile HEIDMANN, CRCN CNRS
• Thierry HEIDMANN, DREM
• Gérard PIERRON, DREM
• Marianne MANGENEY, CRHC CNRS
• Agathe BACQUIN, Researcher
• Grégoire MARTIN, Researcher
• Guillaume MOUSSEAU, Researcher
• Baptiste ROELENS, Researcher
• Jhen TSANG, Researcher
• Maude MARCHAIS, Researcher

ITA :

Publications

Endogenous retroviral envelopes / syncytin genes

Mousseau G, Préault N, Souquère S, Bireau C, Cassonet P, Bacquin A, Beck L, Pierron G, Jacob Y, Dupressoir A, and Heidmann T. The sodium dependent phosphate transporter PiT1/Slc20a1 is the receptor for the endogenous retroviral envelope syncytin-B involved in mouse placenta formation. J Virol 2024 Sep 17 e0091524  Editor's Pick
 

Physiology and Molecular Pathology of Endogenous and Infectious Retroviruses

This team belongs to the UMR 9196 : Physiology and Molecular Pathology of Endogenous and Infectious Retroviruses

The Unit's work, historically focused on retroelements and retroviruses, has made significant contributions to:

Lab members

Researchers / Teacher-researchers / PH:

• Jacques GRILL (MD, PhD, HDR)
• Marie-Anne DEBILY (MCU, Univ. d’Evry Val d’Essonne, HDR)
• David CASTEL (CRCN, INSERM, HDR)
• Gilles VASSAL (PU-PH, Univ. Paris-Saclay, HDR)
• Marco BRUSCHI (Postdoctorant, GR)
• Christelle DUFOUR (PH, GR)
• Léa GUERRINI (PH, GR)

Engineers / Technicians: 

Major publications

• 1: Werbrouck C, Evangelista CCS, Lobón-Iglesias MJ, Barret E, Le Teuff G, Merlevede J, Brusini R, Kergrohen T, Mondini M, Bolle S, Varlet P, Beccaria K, Boddaert N, Puget S, Grill J, Debily MA, Castel D. TP53 Pathway Alterations Drive Radioresistance in Diffuse Intrinsic Pontine Gliomas (DIPG). Clin Cancer Res. 2019 Nov 15; 25(22):6788-6800. doi: 10.1158/1078-0432.CCR-19-0126.

Genomics and oncogenesis of childhood brain tumors

This team belongs to the UMR 981 - Molecular predictors and new targets in oncology

The GOBT team is dedicated to understand the development mechanisms of pediatric brain tumors (in particular gliomas). We are looking for biological markers to identify these tumors more precisely, to understand their origin, to define their prognosis and to invent new treatments.

Lab members

• Gerard Mazón (DR2 Inserm, team co-leader)
• Eric Le Cam (DR2 CNRS, team co-leader)
• Pauline Dupaigne (CRCN Inserm)
• Sonia Baconnais (IR CNRS)
• Clara Basto (PhD student, UPS)
• Amina Serrar (PhD student, UPS)
• Josiane Ammar (PhD student, UPS)
• Tia Adaimy (IE CDD, CNRS)
• Ambre Diquellou-Halbeher (M2 student, Lorraine University)
• Eliot Languerau (M1 student, Jules Verne University)

Major publications

1: Muhammad AA, Basto C, Peterlini T, Guirouilh-Barbat J, Thomas M, Veaute X, Busso D, Lopez B, Mazon G, Le Cam E, Masson JY, Dupaigne P. Life Sci Alliance. 2023 Dec 11;7(3):e202201751. doi: 10.26508/lsa.202201751. Print 2024 Mar. PMID: 38081641

Double strand break repair and Genome Integrity Team

This team belongs to the UMR 9019 Genome Integrity and Cancers.

Lab members

• Murat SAPARBAEV, Research Director, DR1, CNRS;
• Alexandre A. ISHCHENKO, Research Director, DR2, CNRS;
• Regina GROISMAN, CRCN, INSERM;
• Sophie GAD-LAPITEAU, Professor, EPHE ;
• Sophie COUVE, Assistant professor, EPHE ;
• Flore RENAUD-PAITRA, Assistant professor, EPHE ;
• Sophie FERLICOT, PU-PH, clinicien, Université Paris-Saclay ;
• Dominique BLUTEAU, Assistant professor, EPHE ;
• Kévin BOQUET, technician, EPHE;
• Victoria POILLERAT, PhD student, EPHE;