A novel triple therapy shows promising signs of efficacy in localised lung cancer

Villejuif, 23 April 2026

A novel triple therapy shows promising signs of efficacy in localised lung cancer

The MATISSE study, presented by Professor Fabrice Barlesi, CEO of Gustave Roussy, during a plenary session on clinical trials at the AACR congress, evaluated the addition of a new molecule to the therapeutically validated combination already used for certain patients with non-small cell lung cancer. This novel triple therapy has demonstrated initial promising clinical effects.

U1355 RAMO-IT - Molecular Radiotherapy and Therapeutic Innovations - Unit members

U1355 RAMO-IT - Molecular Radiotherapy and Therapeutic Innovations
Unit members

Researchers

  • Dr. Lydia MEZIANI (CRCN, INSERM)
  • Dr. Michele MONDINI (CRCN, INSERM)
  • Dr. Charlotte ROBERT (MCU, Paris Saclay, Gustave Roussy, HDR)

Physicians / Pharmacists / Physicists (interfaces)

  • Dr. Frédéric DHERMAIN (PH, Gustave Roussy)
  • Dr. Sébastien GOUY (PU-PH, Gustave Roussy)
  • Dr. Antonin LEVY (PH, MCU, Gustave Roussy)
  • Dr Elaine LIMKIN (PH, Gustave Roussy)

U1355 RAMO-IT - Molecular Radiotherapy and Therapeutic Innovations - publications

U1355 RAMO-IT - Molecular Radiotherapy and Therapeutic Innovations
Major publications

  • Bockel S, El Aichi M, Sun R, Benzazon N, de Kermenguy F, Veres C, Satragno C, Bidault F, Garcia G, Dhermain F, Deutsch E, Robert C. Integration of white matter tracts in stereotactic brain radiotherapy treatment planning with a fully automated atlas-based pipeline. Comput Biol Med. 2026

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