Adresse

Gustave Roussy
114, rue Édouard-Vaillant
94805 Villejuif Cedex - France

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Tel : +33 (0)1 42 11 42 11

Urgences

Gustave Roussy n'assure que les urgences des patients pris en charge à l'Institut.
Urgences uniquement : +33 (0)1 42 11 50 00

GUSTAVE ROUSSY
1er centre de lutte contre le cancer en Europe, 3 000 professionnels mobilisés

Dynamique de la chromatine et métabolisme dans le cancer

Responsables
Dr Yegor Vassetzky
E-mail

Svetlana Dokudovskaya
E-mail
 

 

Frise de présentation (bandeau): 
Dynamique de la chromatine et métabolisme dans le cancer

Publications majeures

  • Iarovaia, O.V., Minina, E.P., Sheval, E.V., Dokudovskaya, S.S., Razin, S.V. and VASSETZKY, Y.S. (2019) Nucleolus: organizing the functioning of the genome. Trends in Cell Biology, DOI: 10.1016/j.tcb.2019.04.003
  • Harrington CT, Sotillo E, Robert A, Hayer KE, Bogusz AM, Psathas J, Yu D, Taylor D, Dang CV, Klein P, Hogarty MD, Geoerger B, El-Deiry WS, Wiels J, Thomas-Tikhonenko A. (2019) Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma. Leukemia 33:2429-2441 DOI: 10.1038/s41375-019-0454-4
  • Germini, D., Tsfasman, T., Zakharova V.V., Sjakste, N., Lipinski M., and VASSETZKY, Y.S. (2018) A comparison of techniques to evaluate the effectiveness of genome editing. Trends in Biotechnology, 36:147-159 DOI: 10.1016/j.tibtech.2017.10.008
  • Ma, Y., Vassetsky, Y.S., Dokudovskaya, S. (2018) mTORC1 pathway in DNA damage response mTORC1 pathway in DNA damage response. BBA Molecular Cell Research, 1865: 1293-1311. DOI:10.1016/j.bbamcr.2018.06.011
  • El-Amine, R., Germini, D., Zakharova V.V., Tsfasman, T., Sheval, E.V., Louzada, R.A.N., Dupuy, C., Hamade, A., Najjar, F., Bilhou-Nabera, C., Oksenhendler, E., Lipinski M., Chernyak, B.V. and VASSETZKY, Y.S. (2018) HIV-1-Tat protein induces DNA damage in humanperipheralblood B-lymphocytes via mitochondrial ROS production. Redox Biology, 15:97-108 DOI: 10.​1016/​j.​redox.​2017.​11.​024
  • Ma Y., Silveri L., La Cava J. and Dokudovskaya S. (2018) TumorSuppressor NPRL2 induces ROS production and DNA damage response. Sci.Rep. 7: 15311. DOI: 10.1038/s41598-017-15497-0.
  • Germini, D., Tsfasman, T., Klibi M., Pichugin, A., El-Amine, R.,  Iarovaia, O., Bilhou-Nabera, C., Subra, F., Bou Saada, Y., Sukhanova, A., Boutboul, D., Raphaël, M.,  Wiels, J, Razin, S., Bury-Moné, S., Oksenhendler, E., Lipinski M., and VASSETZKY, Y.S. (2017) The HIV-1 Tat protein induces MYC  relocalization next to IGH in normal B-cells. Leukemia, 31:2515-2522 DOI: 10.1038/leu.2017.10
  • Pichugin A.,  Iarovaia O.V., Gavrilov, A.,Sklyar, I., Barinova, N.,  Barinov, A.,  Ivashkin, E.,  Caron, G., Aofouchi, S., Razin, S.V., Fest, T., Lipinski M. and VASSETZKY, Y.S. (2017) The IGH locus relocalizes to a “recombination compartment” in the perinucleolar region of differentiating B-lymphocytes. Oncotarget, 8:40079-40089 DOI:10.18632/oncotarget.16941
  • Allinne J., Pichugin A.,  Iarovaia O.,  Klibi M., Barat A., Zlotek-Zlotkiewicz E., Markozashvili1 D., Petrova N.,  Camara-Clayette V.,  Ioudinkova E., Wiels, J, Razin, S., Ribrag V., Lipinski M., and VASSETZKY, Y.S. (2014) Perinucleolarrelocalization and nucleolin as crucial events in the transcriptional activation of key genes in mantle cell lymphoma. Blood. 123:2044-53 DOI:10.1182/blood-2013-06-510511
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