Adresse

Gustave Roussy
114, rue Édouard-Vaillant
94805 Villejuif Cedex - France

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Tel : +33 (0)1 42 11 42 11

Urgences

Avant toute venue aux urgences, il est impératif de téléphoner au (0)1 42 11 42 11. En cas de venue sans appel préalable, vous serez transféré dans un autre hôpital.

GUSTAVE ROUSSY
1er centre de lutte contre le cancer en Europe, 3 000 professionnels mobilisés

Relations hôte-tumeurs dans les carcinomes ORL

Responsables
Dr Pierre Busson - E-mail
Pr Karim Benihoud - E-mail

Contact
Tél. : +33 (0)1 42 11 45 83
 

 

Frise de présentation (bandeau): 
Relations hôte-tumeurs dans les carcinomes ORL

Publications majeures

  • Xu JX, Zhang R, Huang DJ, Tang Y, Ping LQ, Huang BJ, Huang HQ, Busson P, Li J. (2023). Galectin-9 Facilitates Epstein-Barr Virus Latent Infection and Lymphomagenesis in Human B Cells. Microbiol Spectr. 9:e0493222. doi: 10.1128/spectrum.04932-22.
  • Tran BTT,  Gelin A, Durand S, Texier M, Daste A, Toullec C, Benihoud K, Breuskin I, Gorphe P, Garic F, Brenner C, Le Tourneau C, Fayette J, Niki T, David M, Busson P, Even C. (2022). Plasma galectins and metabolites in advanced head and neck carcinomas: evidence of distinct immune characteristics linked to hypopharyngeal tumors. Oncoimmunology 12, 2150472. doi: 10.1080/2162402X.2022.2150472. 
  • Dekaliuk M, Busson P, Hildebrandt N. (2022) Isothermal Rolling Circle Amplification and Lanthanide-Based FRET for Femtomolar Quantification of MicroRNA. Anal. Sens. e202200073. doi.org/10.1002/anse.202200073
  • Baloche V, Rivière J, Tran TBT, Gelin A, Bawa O, Signolle N, Diop MK, Dessen P, Beq S, David M, Busson P. (2021) Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model. Sci Rep 11, 5227. doi.10.1038/s41598-021-84270-1
  • Tesse A, André FM, Ragot T. (2021) Aluminum particles generated during millisecond electric pulse application enhance adenovirus-mediated gene transfer in L929 cells. Sci Rep. 11, 17725. doi: 10.1038/s41598-021-96781-y
  • Nestić D, Hozić A, Brkljača Z, Butorac A, Pažur K, Jullienne B, Cindrić M, Ambriović-Ristov A, Benihoud K & Majhen D. (2022) Integrin avb3 and disulfide bonds play important roles in NGR-retargeted adenovirus transduction efficiency. Life Sci. 291, 120116. doi: 10.1016/j.lfs.2021.120116.
  • Makowska A, Lelabi N, Nothbaum C, Shen L, Busson P, Tran TTB, Eble M, Kontny U. (2021) Radiotherapy Combined with PD-1 Inhibition Increases NK Cell Cytotoxicity towards Nasopharyngeal Carcinoma Cells. Cells 10, 2458. doi: 10.3390/cells10092458.
  • Boulanger P, Vernhes E, Ducrot N, Lari-Cherif L & Benihoud K. (2021) Production and functionalization of nanoparticles derived from phage T5 and therapeutic uses. Patent deposit WO2021053309A1.
  • Makowska A, Meier S, Shen L, Busson P, Baloche V, Kontny U. (2021) Anti-PD-1 antibody increases NK cell cytotoxicity towards nasopharyngeal carcinoma cells in the context of chemotherapy-induced upregulation of PD-1 and PD-L1. Cancer Immunol Immunother 70, 323-336. doi: 10.1007/s00262-020-02681-x.
  • Benihoud K. & Brenner C. (2021) Profiling the Energy Metabolism at the Cell Subpopulation Level J Cancer Immunol. 3,147-150 (commentaire)
  • Zhang CX, Huang DJ, Baloche V, Zhang L, Xu JX, Li BW, Zhao XR, He J, Mai HQ, Chen QY, Zhang XS, Busson P, Cui J, Li J. (2020) Galectin-9 promotes a suppressive microenvironment in human cancer by enhancing STING degradation. Oncogenesis.9, 65. doi: 10.1038/s41389-020-00248-0.
  • Baloche V, Ferrand FR, Makowska A, Even C, Kontny U, Busson P. (2020) Emerging therapeutic targets for nasopharyngeal carcinoma: opportunities and challenges. Expert Opin Ther Targets 24, 545-558. doi: 10.1080/14728222.2020.1751820 (revue).
  • Dekaliuk M, Qiu X, Troalen F, Busson P, Hildebrandt N. (2019) Discrimination of the V600E mutation in BRAF by Rolling Circle Amplification and Förster Resonance Energy Transfer. ACS Sens. 4: 2786-2793. doi: 10.1021/acssensors.9b01420.
  • Lhuillier C, Barjon C, Baloche V, Niki T, Gelin A, Mustapha R, Claer L. Hoos S, Chiba Y, Ueno M, Hirashima M, Wei M, Morales O, Raynal B, Delhem N, Dellis O and Busson P. (2018) Characterization of neutralizing antibodies reacting with the 213-224 amino-acid segment of human galectin-9. PLoS One  13, e0202512. doi: 10.1371/journal.pone.0202512.
  • Anchim A, Raddi N, Zig L, Perrieau P, Le Goffic R, Ryffel B & Benihoud K. (2018) Humoral responses elicited by adenovirus displaying epitopes are induced independently of the infection process and shaped by the TLR/MyD88 pathway. Frontiers in Immunology 9, 124. doi: 10.3389/fimmu.2018.00124.
  • Bressy C, Majhen D, Raddi N, Jdey W, Cornilleau G, Zig L, Guirouilh-Barbat J, Lopez BS, Bawa O, Opolon P, Grellier E & Benihoud K. (2017) Combined therapy of colon carcinomas with an oncolytic adenovirus and valproic acid. Oncotarget 8, 97344-97360. doi: 10.18632/oncotarget.22107.

 

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