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Adresse

Gustave Roussy
114, rue Édouard-Vaillant
94805 Villejuif Cedex - France

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Tel : +33 (0)1 42 11 42 11

Urgences

Gustave Roussy n'assure que les urgences des patients pris en charge à l'Institut.
Urgences uniquement : +33 (0)1 42 11 50 00

GUSTAVE ROUSSY
1er centre de lutte contre le cancer en Europe, 3 000 professionnels mobilisés

Oncogenèse et progression tumorale du mélanome

Responsable
Dr Mehdi Khaled
Tél. : + 33 (0)1 42 11 37 67

Bâtiment de médecine moléculaire, Niveau 2,
Pièce 236

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Frise de présentation (bandeau): 
Oncogenèse et progression tumorale du mélanome

Publications majeures

  • Golan, T., Parikh, R., Jacob, E., Vaknine, H., Zemser-Werner, V., Hershkovitz, D., Malcov, H., Leibou, S., Reichman, H., Sheinboim, D., Percik, R., Amar, S., Brenner, R., Greenberger, S., Kung, A., Khaled, M., and Levy, C. (2019) Adipocytes sensitize melanoma cells to environmental TGF-beta cues by repressing the expression of miR-211. Sci Signal 12
  • Nordlinger, A. *, Dror, S. *, Elkahloun, A., Del Rio, J., Stubbs, E., Golan, T., Malcov, H., Pricket, T. D., Cronin, J. C., Parikh, S., Labes, S., Thomas, L., Yankovitz, G., Tabach, Y., Levy, C., Samuels, Y., and Khaled, M. (2018) Mutated MITF-E87R in Melanoma Enhances Tumor Progression via S100A4. J Invest Dermatol 138, 2216-2223
    * Co-first author author
  • Malcov-Brog, H., Alpert, A., Golan, T., Parikh, S., Nordlinger, A., Netti, F., Sheinboim, D., Dror, I., Thomas, L., Cosson, C., Gonen, P., Stanevsky, Y., Brenner, R., Perluk, T., Frand, J., Elgavish, S., Nevo, Y., Rahat, D., Tabach, Y., Shen-Orr, S. S.*, Levy, C* and Khaled, M.*. (2018) UV-Protection Timer Controls Linkage between Stress and Pigmentation Skin Protection Systems. Mol Cell 72, 444-456 e447
    * Co-last author and co-corresponding author
  • Thirant, C., Ignacimouttou, C., Lopez, C. K., Diop, M., Le Mouel, L., Thiollier, C., Siret, A., Dessen, P., Aid, Z., Riviere, J., Rameau, P., Lefebvre, C. L., Khaled, M., Leverger, G., Ballerini, P., Petit, A., Raslova, H., Carmichael, C. L., Kile, B. T., Soler, E., Crispino, J. D., Wichmann, C., Pflumio, F., Schwaller, J. U., Vainchenker, W., Lobry, C., Droin, N., Bernard, O. A., Malinge, S., and Mercher, T. (2017) ETO2-GLIS2 Hijacks Transcriptional Complexes to Drive Cellular Identity and Self-Renewal in Pediatric Acute Megakaryoblastic Leukemia. Cancer Cell 31, 452-465
  • Salma, N., Song, J. S., Kawakami, A., Devi, S. P., Khaled, M., Cacicedo, J. M., and Fisher, D. E. (2017) Tfe3 and Tfeb transcriptionally regulate Ppargamma2 expression in adipocytes and mediate adiponectin and glucose levels in mice. Mol Cell Biol
  • Hasmim, M., Janji, B., Khaled, M., Noman, M. Z., Louache, F., Bordereaux, D., Abderamane, A., Baud, V., Mami-Chouaib, F., and Chouaib, S. (2017) Cutting Edge: NANOG Activates Autophagy under Hypoxic Stress by Binding to BNIP3L Promoter. Journal of Immunology 198, 1423-1428
  • Ly, N., Elkhatib, N., Bresteau, E., Pietrement, O., Khaled, M., Magiera, M. M., Janke, C., Le Cam, E., Rutenberg, A. D., and Montagnac, G. (2016) alpha TAT1 controls longitudinal spreading of acetylation marks from open microtubules extremities. Scientific Reports 6, 10
  • Levin, L., Srour, S., Gartner, J., Kapitansky, O., Qutob, N., Dror, S., Golan, T., Dayan, R., Brener, R., Ziv, T., Khaled, M., Schueler-Furman, O., Samuels, Y., and Levy, C. (2016) Parkin Somatic Mutations Link Melanoma and Parkinson's Disease. Journal of Genetics and Genomics 43, 369-379
  • Dror, S., Sander, L., Schwartz, H., Sheinboim, D., Barzilai, A., Dishon, Y., Apcher, S., Golan, T., Greenberger, S., Barshack, I., Malcov, H., Zilberberg, A., Levin, L., Nessling, M., Friedmann, Y., Igras, V., Barzilay, O., Vaknine, H., Brenner, R., Zinger, A., Schroeder, A., Gonen, P., Khaled, M., Erez, N., Hoheisel, J. D., and Levy, C. (2016) Melanoma miRNA trafficking controls tumour primary niche formation. Nature Cell Biology 18, 1006-1017
  • Levy, C., and Khaled, M. (2015) Ecad vitiliGONE. Pigment Cell & Melanoma Research 28, 376-377

 

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